In Matthew 10:16-22, Jesus was given instructions to the disciples about preaching the gospel. Jesus was sending His disciples out by themselves and they needed to know what to expect. He said I’m sending you out in the midst of wolves. But you are to be as wise as serpents and as harmless as doves. They will bring you the councils, governors and kings and they will kill you. If they hated Me, how much more will they hate you. All this is a testimony against them. Jesus said, take no thought what you will say, because the Holy Ghost will give you what say at that time. He said brother will turn against Brother, father against children, children against their parents. But he the endures to the end shall be saved. Jesus is warning us that in this world you will have tribulation. Because we go out into this world of wolves.